Publications
Publications 2024
- Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse
- Lack of SMARCB1 expression characterizes a subset of human and murine peripheral T-cell lymphomas
- Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract
- PITX2 deficiency leads to atrial mitochondrial dysfunction
- Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia
- Human induced pluripotent stem cell–derived atrial cardiomyocytes recapitulate contribution of the slowly activating delayed rectifier currents IKs to repolarization in the human atrium
- Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus
- A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes
- Antibacterial Activities of the Algal Bromophenol Methylrhodomelol Against Pseudomonas aeruginosa
- Monocytes as Targets for Immunomodulation by Regional Citrate Anticoagulation
- Disentangling specific and unspecific components of innate immune memory in a copepod–tapeworm system
Publications 2023
- The Impact of Phase-Specific Macrophage Depletion on Intestinal Anastomotic Healing
- Elemental bioimaging and transcriptomics reveal unchanged gene expression in mouse cerebellum following a single injection of Gadolinium-based contrast agents
- Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy
- Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that
- Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage
- Intracellular fraction of zona pellucida protein 3 is required for the oocyte-to-embryo transition in mice
- Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formation
- MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas
- Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells
- The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
- Group-specific cellular metabolism in Medulloblastoma
- A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice
- The Influence of Apremilast-Induced Macrophage Polarization on Intestinal Wound Healing
- The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects
- Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy
- Standing genetic variation affects phenotypic heterogeneity in an SCN5A-mutation founder population with excess
- DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice
- A genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies
Publications 2022
- Assessment of angiogenesis-related parameters in juvenile idiopathic arthritis-associated uveitis
- Monocyte subpopulation profiling indicates CDK6‑derived cell differentiation and identifies subpopulation‑specific miRNA expression sets in acute and stable coronary artery disease
- Smarcb1 Loss Results in a Deregulation of esBAF Binding and Impacts the Expression of Neurodevelopmental Genes
- The Pogonomyrmex californicus social niche polymorphism is a polygenic trait involving a young supergene
- Stage-specific gene and transcript dynamics in human male germ cells
- Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells
- Cardiac chamber-specific genetic alterations suggest candidate genes and pathways implicating the left ventricle in the pathogenesis of atrial fibrillation
- A synthetic covalent ligand of the C/EBPβ transactivation domain inhibits acute myeloid leukemia cells
- Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
- The conserved transcriptional program of metazoan male germ cells uncovers ancient origins of human infertility
- SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids
- Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
- C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
- The Impact of Varying Food Availability on Gene Expression in the Liver: Testing the Match-Mismatch Hypothesis
- Transcriptional profiles in the mouse amygdala after a cognitive judgment bias test largely depend on the genotype
- Rapid Downregulation of H3K4me3 Binding to Immunoregulatory Genes in Altered Gravity in Primary Human M1
- Transcriptome analyses in infertile men reveal germ cell–specific expression and splicing patterns
- Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent
- Whole-genome sequencing of artificial single-nucleotide variants induced by DNA degradation in biological crime
- Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health
- Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction
- A balanced Oct4 interactome is crucial for maintaining pluripotency
Publications 2021
- Gravitational Force—Induced 3D Chromosomal Conformational Changes Are Associated with Rapid Transcriptional Response in Human T Cells
- The proteome, not the transcriptome, predicts that oocyte superovulation affects embryonic phenotypes in mice
- The COP9 signalosome subunit 3 is necessary for early embryo survival by way of a stable protein deposit in mouse oocytes
- The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice
- A genetic variant alters the secondary structure of the lncRNA H19 and is associated with dilated cardiomyopathy
- The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus
- Evolutionarily conserved transcriptional landscape of the heart defining the chamber specific physiology
- SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation
- Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier
- Rapid Transient Transcriptional Adaptation to Hypergravity in Jurkat T Cells Revealed by Comparative Analysis of Microarray and RNA-Seq Data
- Climate change facilitates a parasite’s host exploitation via temperature-mediated immunometabolic processes
- The genetic landscape of choroid plexus tumors in children and adults
- An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma
- The bacterial biocontrol agent Paenibacillus alvei K165 confers inherited resistance to Verticillium dahliae
Publications 2020
- ARABIDOMICS—A new experimental platform for molecular analyses of plants in drop towers, on parabolic flights, and sounding rockets
- Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta-adrenergic stimulation
- ADAMTS12, a new candidate gene for pediatric stroke
- Transcriptome analysis of primary podocytes reveals novel calcium regulated regulatory networks
- Glioma escape signature and clonal development under immune pressure
- Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis
- Monitoring Endothelin-A Receptor Expression during the Progression of Atherosclerosis
- Threonine Phosphorylation of IκBζ Mediates Inhibition of Selective Proinflammatory Target Genes
- Rapid Cellular Perception of Gravitational Forces in Human Jurkat T Cells and Transduction into Gene Expression Regulation
- Impact of IL1RN Variants on Response to Interleukin-1 Blocking Therapy in Systemic Juvenile Idiopathic Arthritis
- Synergistic Signaling of TLR and IFNα/β Facilitates Escape of IL-18 Expression from Endotoxin Tolerance
- Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance
- RNA Sequencing of Collecting Duct Renal Cell Carcinoma Suggests an Interaction between miRNA and Target Genes and a Predominance of Deregulated Solute Carrier Gene
Publications 2019
- Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice
- Transcriptomic and proteomic analysis of iris tissue and aqueous humor in juvenile idiopathic arthritis-associated uveitis
- Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution
- A framework for TRIM21-mediated protein depletion in early mouse embryos: recapitulation of Tead4 null phenotype over three days
- Blood transcriptome analysis in a buck-ewe hybrid and its parents
- Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity
- Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin–positive Staphylococcus aureus Colonization in African Pygmies
- Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors
Publications 2018
- Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells
- The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation
- Nuclear YAP localization as a key regulator of podocyte function
- Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis
- Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
- Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease
- Transcriptional Homeostasis of Oxidative Stress-Related Pathways in Altered Gravity
Publications 2017
- Dynamic gene expression response to altered gravity in human T cells
- The Beaver’s Phylogenetic Lineage Illuminated by Retroposon Reads
- Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4
- Single-cell gene expression analysis reveals diversity among human spermatogonia
- Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism
Publications 2016