Publications PubMed

Fouzia Bano, Laura Soria-Martinez, Dominik van Bodegraven, Konrad Throsteinsson, Anna M Brown, Ines Fels, Nicole L Snyder, Marta Bally, Mario Schelhaas. (2024)
Site-specific sulfations regulate the physicochemical properties of papillomavirus-heparan sulfate interactions for entry
Sci Adv. 2024 Oct 4;10(40):eado8540.

Sharafudheen Pottanam Chali, Jaana Westmeier, Franziska Krebs, Shuai Jiang, Friederike Pauline Neesen, Doğa Uncuer, Mario Schelhaas, Stephan Grabbe, Christian Becker, Katharina Landfester, Kerstin Steinbrink (2024).
Albumin nanocapsules and nanocrystals for efficient intracellular drug release
Nanoscale Horiz. doi: 10.1039/d4nh00161c.
 

Freya Molenberghs, Marlies Verschuuren, Lauran Vandeweye, Sarah Peeters, Johannes J Bogers, Claudina Perez Novo, Wim Vanden Berghe, Hans De Reu, Nathalie Cools, Mario Schelhaas, Winnok H De Vos (2024).  
Lamin B1 curtails early human papillomavirus infection by safeguarding nuclear compartmentalization and autophagic capacity
Cell Mol Life Sci. 14;81(1):141.
 

Rizzato M, Mao F, Chardon F, Lai KY, Villalonga-Planells R, Drexler HCA, Pesenti ME, Fiskin M, Roos N, King KM, Li S, Gamez ER, Greune L, Dersch P, Simon C, Masson M, Van Doorslaer K, Campos SK, Schelhaas M. (2023) .
Master mitotic kinases regulate viral genome delivery during papillomavirus cell entry.
Nat Commun. 14:355

Molenberghs F, Verschuuren M, Barbier M, Bogers JJ, Cools N, Delputte P, Schelhaas M, De Vos WH.(2022) . 
Cells infected with human papilloma pseudovirus display nuclear reorganization and heterogenous infection kinetics.
Cytometry A. 101:1035-1048. 

Huisman Y, Uphoff K, Berger M, Dobrindt U, Schelhaas M, Zobel T, Bussmann J, van Impel A, Schulte-Merker S.(2021) .
Meningeal lymphatic endothelial cells fulfill scavenger endothelial cell function and cooperate with microglia in waste removal from the brain.
Glia. 70:35-49.

Lai KY, Rizzato M, Aydin I, Villalonga-Planells R, Drexler HCA, Schelhaas M.(2021).
A Ran-binding protein facilitates nuclear import of human papillomavirus type 16.
PLoS Pathog. 11;17:e1009580.

May Bosso M, Prelli Bozzo C, Hotter D, Volcic M, Stürzel CM, Rammelt A, Ni Y, Urban S, Becker M, Schelhaas M, Wittmann S, Christensen MH, Schmidt FI, Gramberg T, Sparrer KMJ, Sauter D, Kirchhoff F. (2020).
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
PLoS Pathog. 6;16:e1008752.

Bannach C, Brinkert P, Kühling L, Greune L, Schmidt MA, Schelhaas M. (2020)
Epidermal growth factor receptor and Abl2 kinase regulate distinct steps of Human papillomavirus type 16 endocytosis.
J Virol. 18;94:e02143-19.

Soria-Martinez L, Bauer S, Giesler M, Schelhaas S, Materlik J, Janus K, Pierzyna P, Becker M, Snyder NL, Hartmann L, Schelhaas M. (2020).
Prophylactic Antiviral Activity of Sulfated Glycomimetic Oligomers and Polymers.
J Am Chem Soc. 18;142:5252-5265

Schelhaas M. (2020).
Interview-Mario Schelhaas.
Cell Microbiol. 22:e13139.

Weiss VU, Pogan R, Zoratto S, Bond KM, Boulanger P, Jarrold MF, Lyktey N, Pahl D, Puffler N, Schelhaas M, Selivanovitch E, Uetrecht C, Allmaier G (2019).
Virus-like particle size and molecular weight/mass determination applying gas-phase electrophoresis (native nES GEMMA).
Anal Bioanal Chem. 411:5951-5962.

Becker M, Dominguez M, Greune L, Soria-Martinez L, Pfleiderer MM, Schowalter R, Buck CB, Blaum BS, Schmidt MA, Schelhaas M (2019).
Infectious Entry of Merkel Cell Polyomavirus.
J. Virol. 93:e02004-18.

Becker M, Dominguez M, Greune L, Soria-Martinez L, Pfleiderer MM, Schowalter R, Buck CB, Blaum BS, Schmidt MA, Schelhaas M (2019).
Infectious Entry of Merkel Cell Polyomavirus.
J. Virol. 93:e02004-18.

Stehle T, Peters T, Hartmann L, Schelhaas M (2018).
Glycans Controlling Virus Infections: Meeting Report on the 1st International Symposium on Glycovirology Schöntal, Germany, 02⁻04 May 2018.
Viruses 10, 636.

Stradal TE, Schelhaas M (2018).
Actin dynamics in host–pathogen interaction.
FEBS Lett. 2018.

Becker M, Greune L, Schmidt MA, Schelhaas M (2018).
Extracellular conformational changes in the capsid of human papillomaviruses contribute to asynchronous uptake into host cells.
J. Virol. 92:e02106-17.

Schelhaas M (2017).
Viruses and cancer: molecular relations and perspectives.
Biol Chem. 398, 815-816.

Aydin I, Villalonga-Planells R, Greune L, Bronnimann MP, Calton CM, Becker M, Lai K-Y, Schmidt MA, Schelhaas M (2017).
A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for miotic nuclear entry.
PLoS pathog. 13, e1006308. 

Aydin I, Schelhaas M (2016).
Viral genome tethering to host cell chromatin: cause and consequences.
Traffic 17, 327-340. 

Samperio Ventayol P, Schelhaas M (2015).
Fluorescently labeled human papillomaviruses in virus entry experiments.
Curr Protocol Microbiol. 14B, 4.1-14B, 4.22. 

Cerqueira C, Samperio Ventayol P, Vogeley C, Schelhaas M (2015).
Kallikrein-8 proteolytically processes human papillomaviruses in the extracellular space to facilitate virus entry.
J. Virol. 89, 7038-7052. 

Kühling L, Schelhaas M (2014).
Systematic analysis of endocytosis by cellular perturbations.
Methods Mol. Biol. 1174, 19-46. 

Day PM, Schelhaas M (2014).
Concepts of papillomavirus entry into host cells.
Curr. Opin. Virol. 4, 24-31. 

Spoden G, Kühling L, Cordes N, Frenzel B, Sapp M, Boller K, Florin L, Schelhaas M (2013).
Human papillomavirus types -16, -18, and -31 share similar requirements for entry.
J. Virol. 87, 7765-7773. 

Cerqueira C, Liu Y, Kühling L, Chai W, Hafezi W, van Kuppevelt T, Kühn JE, Feizi T, Schelhaas M (2013).
Heparin increases the infectivity of Human Papillomavirus Type 16 independent of cell surface proteoglycans and induces L1 epitope exposure.
Cell Microbiol. 15, 1818-36.

Snijder, B, Sacher R, Rämö P, Liberali P, Mench K, Wolfrum N, Burleigh L, Scott CC, Verheije MH, Mercer J, Moese S, Heger T, Theusner CK, Jurgeit A, Lamparter D, Balistreri G, Schelhaas M, De Haan CA, Marjomäki V, Hyypiä T, Rottier P, Sodeik B, Marsh M, Gruenberg J, Amara A, Greber U, Helenius A, Pelkmans L (2012).
Single-cell analysis of population context advances RNAi screening at multiple levels.
Mol. Syst. Biol. 8, 579. 

Raff AB, Woodham AW, Raff LM, Skeate JG, Yan L, Da Silva DM, Schelhaas M, Kast WM (2013).
The evolving field of human papillomavirus receptor research: a review of binding and entry.
J. Virol., 87, 6062-6072. 

Cerqueira C, Schelhaas M (2012).
Principles of polyoma- and papillomavirus uncoating.
Med. Microbiol. Immunol. 201, 427-436. 

Ewers H, Schelhaas M (2012).
Analysis of virus entry and cellular membrane dynamics by single particle tracking.
Methods Enzymol. 506; 63-80. (Volume 506: P. Michael Conn, ed.: Imaging of Live Cells in Health and Disease) 

Schelhaas M (2010).
Come in and take your coat off - how host cells provide endocytosis for virus entry.
Cell. Microbiol. 12, 1378-88. 

Mercer J, Schelhaas M, Helenius A (2010).
Virus entry by endocytosis.
Annu. Rev. Biochem. 79, 803-833. 

Schelhaas M, Ewers H, Rajamäki M, Day P, Schiller J, Helenius A (2008).
HPV-16 entry: retrograde cell surface transport along actin-rich protrusions.
PLoS pathog. 4, e1000148. 

Schelhaas M, Malmström J, Pelkmans L, Haugstetter J, Ellgaard L, Grünewald K, Helenius A (2007).
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells.
Cell 131, 516–529. 

Hoppe S*, Schelhaas M*, Liebig T, Knebel-Mörsdorf D  *equal contribution (2006).
Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells.
J. gen. Virol. 87, 3483-3494. 

Quadt I, Günther AK, Voß D, Schelhaas M, Knebel-Mörsdorf D (2006).
TATA-binding protein and TBP-associated factors during herpes simplex virus type 1 infection: localization at viral DNA replication sites.
Virus Res. 115, 207–213. 

Schelhaas M, Jansen M, Haase I, Knebel-Mörsdorf D (2003).
Herpes Simplex Virus Type 1 exhibits a tropism for basal entry in polarised epithelial cells.
J. gen. Virol. 84, 2473-2484.