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Quispe Haro, J. J.; Chen, F.; Los, R.; Shi, S.; Sun, W.; Chen, Y.; Idema, T.; Wegner, S.V.
Optogenetic Control of Bacterial Cell‐Cell Adhesion Dynamics: Unraveling the Influence on Biofilm Architecture and Functionality
Advanced Science, 2024, 2310079
Luo, Z.; Cheng, X.; Feng, B.; Fan, D.; Liu, X.; Xie, R.; Luo, T.; Wegner, S. V.; Ma, D.; Chen, F.; Zeng, W.
Engineering Versatile Bacteria-Derived Outer Membrane Vesicles: An Adaptable Platform for Advancing Cancer Immunotherapy
Advanced Science, 2024, 2400049.
Raab, C. A.; Wegner, S. V.
Reversible Photoregulation of Cell–Cell Adhesions With Opto-E-cadherin
Bio-protocol, 2024, 14 (10)
Song, CX; Jia, G.; Wegner, S.; Yi, C.
Chemical Biology of Nucleic Acid Modifications–Celebrating the Groundbreaking Contributions of Chuan He
Israel Journal of Chemistry, 2024, 64 (3-4), e202400036
Fan, D.; Liu, X.; Ren, Y.; Luo, Z.; Li, Y.; Dong, J.; Wegner, S. V.; Chen, F.; Zeng, W
Harnessing antimicrobial peptide-coupled photosensitizer to combat drug-resistant biofilm infections through enhanced photodynamic therapy
Acta Pharmaceutica Sinica B, 2024, 14 (4), 1759-1771
Di Iorio, D.; Wegner, S. V.
Dynamic Light-Induced Protein Patterns at Model Membranes
Journal of Visualized Experiments, 2024, e66531. (Special Issue on bottom-up synthetic biology)
Nzigou Mombo, B.; Bijonowski, B. M.; Raab, C. A.; Niland, S.; Brockhaus, K.; Müller, M.; Eble, J. A.; Wegner, S. V.
Reversible Photoregulation of Cell-Cell Adhesions with Opto-E-cadherin.
Nat. Commun. 2023, 14, 6292.
Ji, Y.; Heidari, A.; Nzigou Momboa, B.; Wegner, S. V.
Photoactivation of LOV domains with chemiluminescence
Chem. Sci. 2023, DOI: 10.1039/D3SC04815B.
Chen, F.; Dong, J.; Sun, W.; Di Iorio, D.; Wegner, S. V.; Zeng, W.
Construction of smart materials for biomedical application.
Front. Bioeng. Biotechnol. 2023 11:1278243.
Quise Haro, J. J.; Wegner, S.V.
An Adenosylcobalamin Specific Whole‐Cell Biosensor
Adv. Healthcare Mater. 2023, 2300835.
Ji, Y.; Chakraborty, T.; Wegner, S. V.
Self-Regulated and Bidirectional Communication in Synthetic Cell Communities
ACS Nano 2023, 17, 10, 8992–9002
Di Iorio, D.; Bergmann, J.; Higashi, S. L.; Hoffmann, A.; Wegner, S. V.
A disordered tether to iLID improves photoswitchable protein patterning on model membranes
Chem. Comm. 2023, 59 (29), 4380-4383.
Manikowski, D.; Steffes, G.; Froese, J.; Exner, S.; Ehring, K.; Gude, F.; Di Iorio, D.; Wegner, S. V.; Grobe, K.
Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions
Front. Mol. Biosci. 2023, 10, 1130064.
Zheng, Y.; Wegner, T.; Di Iorio, D.; Pierau, M.; Glorius, F.; Wegner, S. V.
NTA-Cholesterol Analogue for the Nongenetic Liquid-Ordered Phase-Specific Functionalization of Lipid Membranes with Proteins
ACS Chem. Biol. 2023, 18, 6, 1435–1443
Heidari, A.; Sentürk, O. I.; Yang, S.; Joesaar, A.; Gobbo, P.; Mann, S.; de Greef, T. F. A.; Wegner S. V.
Orthogonal Light‐Dependent Membrane Adhesion Induces Social Self‐Sorting and Member‐Specific DNA Communication in Synthetic Cell Communities
Small 2023, 202206474.
Gude, F.; Froese, J.; Manikowski, D.; Di Iorio, D.; Grad, J. N.; Wegner, S. V.; Hoffmann, D.; Kennedy, M.; Richter, R. P.; Steffes, G.; Grobe, K.
Hedgehog is relayed through dynamic heparan sulfate interactions to shape its gradient
Nat. Commun. 2023, 14, 758.
Liu, X.; Fan, D.; Ren, Y.; Huang, S.; Ding, J.; Liu, M.; Wegner, S. V.; Hou, J.; Rong, P.; Chen, F.; Zeng, W.
Photo-Activable Organosilver Nanosystem Facilitates Synergistic Cancer Theranostics
ACS Appl. Mater. Interfaces 2023, 15, 1, 711–722.
Di Iorio, D.; Wegner, S. V.
Towards applications of synthetic cells in nanotechnology
Current Opinion in Chemical Biology 2022, 68, 102145.
Chen, F.; Wegner S. V.
Photoswitchable Bacterial Adhesions for the Control of Multicellular Behavior
Engineered Living Materials 2022, 129-148 (Wiley)
Liu, X.; Fan, D.; Feng, X.; Zheng, Y.; Wegner, S. V.; Liu, M.; Chen, F.; Zeng W.
Breaching Bacterial Biofilm Barriers: Efficient Combinatorial Theranostics for Multidrug-Resistant Bacterial Biofilms with a Novel Penetration-Enhanced AIEgen Probe
ACS Applied Materials & Interfaces 2022 14 (37), 41671-41683
Chen, F.; Zeng, W.; Wegner, S. V.
Ultrasound-activated bacteria with thermostat controls as living therapeutics
Matter 2022, 5 (8), 2416-2419
Kaspar, C.; Ravoo, B. J.; van der Wiel, W. G.; Wegner, S. V.; Pernice, W. H. P.
The rise of intelligent matter
Nature 2021, 594, 345–355.
Chakraborty, T.; Wegner, S. V.*
Cell to Cell Signaling Through Light in Artificial Cell Communities: Glowing Predator Lures Prey
ACS Nano 2021, 15, 9434–9444. ACS Editors’ Choice
Nzigou Mombo, B.; Bijonowski, B. M.; Rasoulinejad, S.; Mueller, M.; Wegner, S. V.*
Spatiotemporal Control Over Multicellular Migration Using Green Light Reversible Cell–Cell Interactions
Adv. Biology 2021, 5, 2000199.
Lenders, M.; Scharnetzki, D.; Heidari, A.; Di Iorio, D.; Wegner, S. V.; Brand, E.
Generation and Characterization of a Polyclonal Human Reference Antibody to Measure Anti-Drug Antibody Titers in Patients with Fabry Disease
Int. J. Mol. Sci. 2021, 22, 2680.
Stengelin, E.; Nzigou Mombo, B.; Mondeshki, M.; Beltramo, G. L.; Lange, M. A.; Schmidt, P.; Frerichs, H.; Wegner, S. V.; Seiffert, S.
Rational Design of Thermoresponsive Microgel Templates with Polydopamine Surface Coating for Microtissue Applications
Macromol. Biosci. 2021, 2100209.
M. Mueller; Wegner, S. V.*
Wie Licht beim Aufbau von Geweben helfen kann
BIOspektrum, 2020, 26 (4), 362.
D. Xu; A. J. Heck; S. L. Kuan; T. Weil; Wegner, S. V.*
Precise tetrafunctional streptavidin bioconjugates towards multifaceted drug delivery systems
Chem. Commun., 2020,56, 9858-9861.
F. Chen; R. L. Warnock; J. R. Van der Meer; Wegner, S. V.*
Bioluminescence-Triggered Photoswitchable Bacterial Adhesions Enable Higher Sensitivity and Dual-Readout Bacterial Biosensors for Mercury.
ACS Sens. 2020, 5, 2205–2210.
D. Xu; C. Kleineberg; T. Vidaković-Koch; Wegner, S. V.*
Multistimuli Sensing Adhesion Unit for the Self-Positioning of Minimal Synthetic Cells
Small, 2020, 2002440.
S. Rasoulinejad; M. Mueller; B. Nzigou Mombo; Wegner, S. V.*
Orthogonal Blue and Red Light Controlled Cell–Cell Adhesions Enable Sorting-out in Multicellular Structures
ACS Synth. Biol., 2020, 9, 2076–2086.
Mueller, M.; Rasoulinejad, S.; Garg, S.; Wegner, S. V.*
The Importance of Cell–Cell Interaction Dynamics in Bottom-Up Tissue Engineering: Concepts of Colloidal Self-Assembly in the Fabrication of Multicellular Architectures
Nano Lett., 2020, 20, 4, 2257.
Steinkühler, J.; Knorr, R. L.; Zhao, Z.; Bhatia, T.; Bartelt, S. M.; Wegner, S. V.; Dimova, R.; Lipowsky, R.
Controlled division of cell-sized vesicles by low densities of membrane-bound proteins
Nat. Commun., 2020, 11, 905.
Xu, D.; Wegner, S. V.*
Multifunctional streptavidin–biotin conjugates with precise stoichiometries
Chem. Sci., 2020, 11, 4422.
Xu, D.; Ricken, J.; Wegner, S. V.*
Turning Cell Adhesions ON or OFF with High Spatiotemporal Precision using the Green Light Responsive Protein CarH
Chem. Eur. J., 2020, DOI: 10.1002/chem.202001238
Chen, F.; Wegner, S. V.*
Blue-Light-Switchable Bacterial Cell–Cell Adhesions Enable the Control of Multicellular Bacterial Communities
ACS Syn. Bio., 2020, 9, 1169.
Liu, J.; Ye, L.; Sun, Y.; Hu, M.; Chen, F.; Wegner, S. V.; Mailänder, V.; Steffen, W.; Kappl, M.; Butt, H.-J.
Elastic Superhydrophobic and Photocatalytic Active Films Used as Blood Repellent Dressing
Adv. Mater., 2020, 1908008.
Sentürk,O. I.; Schauer, O.; Chen, F.; Sourjik, V.; Wegner S. V.*
Red/Far‐Red Light Switchable Cargo Attachment and Release in Bacteria‐Driven Microswimmers
Adv. Healthc. Mater., 2020, 9,1900956
Mutschler, H.; Robinson, T.; Tang, T. Y. D.; Wegner, S. V.
Special Issue on Bottom‐Up Synthetic Biology
ChemBioChem, 2019, DOI: 10.1002/cbic.201900507
Ye, L.; Chen, F.; Liu, J.; Gao, A.; Kircher, G.; Liu, W.; Kappl, M.; Wegner, S. V.; Butt, H. J.; Steffen, W.
Responsive Ionogel Surface with Renewable Antibiofouling Properties
Macromol. Rapid Commun., 2019, DOI: 10.1002/marc.201900395.
Chakraborty, T.; Bartelt, S. M.; Steinkühler, J.; Dimova, R.; Wegner S. V.*
Light controlled cell-to-cell adhesion and chemical communication in minimal synthetic cells
Chem. Comm., 2019, 55, 9448.
Sentürk, O. I.; Chervyachkova, E.; Ji, Y.; Wegner, S. V.*
Independent Blue and Red Light Triggered Narcissistic Self‐Sorting Self‐Assembly of Colloidal Particles
Small, 2019, 15, 1901801.
Xu, D.; Bartelt, S. M.; Rasoulinejad, S.; Chen, F.; Wegner, S. V.*
Green light lithography: a general strategy to create active protein and cell micropatterns
Mater. Horiz., 2019, 6, 1222.
Kou, S.; Yang, X.; Yang, Z.; Liu, X.; Wegner, S. V.; Sun F.
Cobalt-Cross-Linked, Redox-Responsive Spy Network Protein Hydrogels
ACS Macro Letters, 2019, 8, 773.
Bartelt, S. M.; Chervyachkova, E.; Ricken, J.; Wegner, S. V.*
Mimicking Adhesion in Minimal Synthetic Cells
Adv. Biosys. 2019, 1800333.
Ricken, J.; Medda, R.; Wegner, S. V.*
Photo-ECM: A Blue Light Photoswitchable Synthetic Extracellular Matrix Protein for Reversible Control over Cell–Matrix Adhesion
Adv. Biosys. 2019, 1800302.
Yüz, S. G.; Rasoulinejad, S.; Mueller, M.; Wegner, A. E.; Wegner, S. V.*
Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering
Adv. Biosys. 2019, 1800310.
Chen, F.; Ricken, J.; Xu, D.; Wegner, S.V.*
Bacterial Photolithography: Patterning biofilms with high spatiotemporal control using photocleavable adhesion molecules
Adv. Biosys. 2019, 1800269.
Bartelt, S.M.; Steinkühler, J.; Dimova, R.; Wegner, S.V.*
Light guided motility of a minimal synthetic cell
Nano Lett., 2018, 18, 7268–7274
Ye, W.; Götz, M.; Celiksoy, S.; Tüting, L.; Ratzke, C.; Prasad, J.; Ricken, J.; Wegner, S.V.; Ahijado-Guzman, R.; Hugel, T.; Sönnichsen, C.
Conformational Dynamics of a Single Protein Monitored for 24 h at Video Rate
Nano Lett. 2018, 18, 6633−6637
Yüz, S.G.; Ricken, J.; Wegner, S.V.*
Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions
Adv. Sci. 2018, 5, 1800446
Ye, W.; Celiksoy, S.; Jakab, A.; Khmelinskaia, A.; Heermann, T.; Raso, A.; Wegner, S. V.; Rivas, G.; Schwille, P.; Ahijado-Guzmán, R.; Sönnichsen, C.
Plasmonic Nanosensors Reveal a Height Dependence of MinDE Protein Oscillations on Membrane Features
J. Am. Chem. Soc., 2018, 140, 17901.
Chervyachkova, E.; Wegner, S.V.*
Reversible Social Self-Sorting of Colloidal Cell-Mimics with Blue Light Switchable Proteins
ACS Synth. Biol. 2018, 7, 1817–1824.
Bartelt, S.M.; Chervyachkova, E.; Steinkühler, J.; Ricken, J.; Wieneke, R.; Tampe, R.; Dimova R.; Wegner, S.V.*
Dynamic blue light-switchable protein patterns on giant unilamellar vesicles
Chem. Comm. 2018, 54, 948–951.
Lima, A.M.; Wegner, S.V.; Martins Cavaco, A.C.; Estevao-Costa, M. I.; Sanz-Soler, R.; Niland, S.; Nosov, G.; Klingauf, J.; Spatz, J.P.; Eble, J.A.
The spatial molecular pattern of integrin recognition sites and their immobilization to colloidal nanobeads determine α2β1 integrin dependent platelet activation
Biomaterials 2018, 167, 107–120.
Morsbach, S.; Gonella, G.; Mailänder, V.; Wegner, S.V.; Wu, S.; Weidner, T.; Berger, R.; Koynov, K.; Vollmer, D.; Encinas, N.; Kuan, S. L.; Weil, T.; Bonn, M.; Butt H.-J.; Landfester, K.
Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
Angew. Chem. Intl. Ed. 2018, 57,12626.
Schwille, P.; Spatz, J.P.; Landfester, K.; Bodenschatz, E.; Herminghaus, S.; Sourjik, V.; Erb, T.; Bastiaens, P.; Lipowsky, R.; Hyman, A.; Dabrock, P.; Baret, J.-P.; Vidakovic-Koch, T.; Bieling, P.; Dimova, R.; Mutschler, H.; Robinson, T.; Tang, T.-Y.D.; Wegner, S.V.; Sundmacher, K.
MaxSynBio – Avenues towards creating cells bottom-up
Angew. Chem. Intl. Ed. 2018, 57, 13382.
Chen, F.; Wegner, S.V.*
Blue Light Switchable Bacterial Adhesion as a Key Step toward the Design of Biofilms
ACS Synth. Biol. 2017, 6, 2170–2174.
Migliorini, E.; Horn, P.; Haraszti, T.; Wegner, S.V.; Hiepen, C.; Knaus, P.; Richter, R.P.; Cavalcanti-Adam, E.A.
Enhanced Biological Activity of BMP-2 Bound to Surface-Grafted Heparan Sulfate
Adv. Biosys. 2017, 1, 1600041.
Wegner, S.V.*; Schenk, F.C.; Witzel, S.; Bialas, F.; Spatz, J.P.
Cobalt Cross-Linked Redox-Responsive PEG Hydrogels: From Viscoelastic Liquids to Elastic Solids
Macromolecules, 2016, 49, 4229−4235.
Wegner, S.V.*; Schenk, F.C.; Spatz, J.P.
Cobalt(III)-Mediated Permanent and Stable Immobilization of Histidine-Tagged Proteins on NTA-Functionalized Surfaces
Chem. Eur. J., 2016, 22, 3156–3162.
Wegner, S.V.*; Sentürk, O.I.; Spatz, J.P.
Photocleavable linker for the patterning of bioactive molecules
Sci. Rep., 2015, 5,18309.
Song, Y.; Yang, M.; Wegner, S.V.; Zhao, J.; Zhu, R.; Wu, Y.; He, C.; Chen, P.R.
A genetically encoded FRET sensor for intracellular Heme
ACS Chem. Biol., 2015, 10, 1610–1615.
Schenk, F.C.; Boehm, H.; Spatz, J.P.; Wegner, S.V.*
Dual-functionalized nanostructured bio-interphases by click-chemistry
Langmuir, 2014, 30, 6897–6905.
Poor, C.B.#; Wegner, S.V.#; Li, H.#; Dlouhy, A.C.; Schuermann, J.P.; Sanishvili, R.; Hinshaw, J.R.; Riggs-Gelasco, P.; Outten, C.E.; He, C. (# Authors contributed equally.)
Molecular mechanism and structure of the S. cerevisiae iron regulator Aft2
Proc. Natl. Acad. Sci.U.S.A., 2014, 111, 4043–4048.
Mateescu, M.; Nuss, I.; Southan, A.; Messenger, H.; Wegner, S.V.; Kupka, J.; Bach, M.; Tovar, G.E.M.; Boehm, H.; Laschat, S.
Synthesis of Pyridine Acrylates and Acrylamides and Their Corresponding Pyridinium Ions as Versatile Cross-Linkers for Tunable Hydrogels
Synthesis, 2014, 46,1243–1253.
Hagel, V.; Mateescu, M.; Southan, A.; Wegner, S.V.; Nuss, I.; Haraszti, T.; Kleinhans, C.; Schuh, C.; Spatz, J.P.; Kluger, P.J.; Bach, M.; Tussetschläger, S.; Tovar, G.E.M.; Laschat, S.; Boehm, H.
Desmosine-Inspired Cross-Linkers for Hyaluronan Hydrogels
Sci. Rep. 2013, 3, 2043.
Wegner, S.V.; Spatz J.P.
Cobalt(III) as a Stable and Inert Mediator Ion between NTA and His6-tagged Proteins
Angew. Chem. Intl. Ed. 2013, 52, 7593–7596.
Southan, A.; Mateescu, M.; Hagel, V.; Bach, M.; Schuh, C.; Kleinhans, C.; Kluger, P.J.; Tussetschläger, S.; Nuss, I.; Haraszti, T.; Wegner, S.V.; Spatz, J.P.; Boehm, H.; Laschat, S.; Tovar, G.E.M.
Towards Controlling the Formation, Degradation Behavior and Properties of Hydrogels Synthesized by Aza-Michael Reactions
Macromol. Chem. Phys. 2013, 214, 1865–1873.
Liu, J.; Karpus, J.; Wegner, S.V.; Chen, P.R.; He, C.
Genetically Encoded Copper(I) Reporters with Improved Response for Use in Imaging
J. Am. Chem. Soc., 2013, 135, 3144–3149.
Noga, M.; Edinger, D.; Kläger, R.; Wegner, S.V.; Spatz, J.P.; Wagner, E.; Winter, G.; Besheer, A.
The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes
Biomaterials, 2013, 34, 2530–2538.
Özçubukçu, S.; Mandal, K.; Wegner, S.V.; Jensen, M. P.; He, C.
Selective Recognition of Americium by Peptide-Based Reagents
Inorg. Chem., 2011, 50, 7937–7939.
Wegner, S.V.; Sun, F.; Hernandez, N.; He, C.
The Tightly Regulated Copper Window in Yeast
Chem. Comm., 2011, 47, 2571–2573.
Wegner, S.V.; Ertem, E.; Sunbul, M.; He, C.
Metal-Binding Properties of Hpn from Helicobacter pylori and Implications for the Therapeutic Activity of Bismuth
Chemical Science, 2011, 2, 451–456.
Wegner, S.V.; Arslan, H.; Sunbul, M.; Yin, J.; He, C.
Dynamic Copper(I) Imaging in Mammalian Cells with a Genetically Encoded Fluorescent Copper(I) Sensor
J. Am. Chem. Soc. 2010, 132, 2567–2569.
Wegner, S.V.; Boyaci, H.; Chen, H.; Jensen, M.; He, C.
Engineering A Uranyl Specific Binding Protein from NikR
Angew. Chem. Intl. Ed. 2009, 48, 2339–2341.
Featured in Science Editors’ Choice. Deutschlandfunk, Forschung Aktuell, 13.03.2009, Uran einen Korb geben
Wegner, S.V.; Okesli, A.; Peng, C.; He, C.
Design of an Emission Ratiometric Biosensor from MerR Family Proteins: A Sensitive and Selective Sensor for Hg2+
J. Am. Chem. Soc. 2007, 129, 3474–3475.