Robert-Koch-Str. 27 a
+ 49 251-83-58118 (phone)
+ 49 251-83-55551 (fax)
Nicole.Rychlik@ukmuenster.de

  • Curriculum vitae

    Scientific activities

    04/2021 – dato PhD student, Institute of Physiology I, University of Münster
    10/2019 – 11/2020 Scientific assistant,
    Prof. P. Küry and PD M. Gliem, Department of Neurology, Uniklinikum, Düsseldorf
    05/2018 – 07/2019 Master student,
    Prof. P. Küry, Department of Neurology, Uniklinikum, Düsseldorf
    10/2018 – 02/2019 Scientific assistant,
    Prof. P. Bauer, Institute of Botany, Heinrich-Heine-University, Düsseldorf
    Students tutoring in Botany
    10/2017 – 02/2018 Scientific assistant,
    Prof. P. Bauer, Institute of Botany, Heinrich-Heine-University, Düsseldorf
    Students tutoring in Botany
    10/2016 – 02/2017 Student assistant, Prof. P. Bauer, Institute of Botany, Heinrich-Heine-University, Düsseldorf
    Students tutoring in Botany

    Part-time job

    08/2019 – dato Assistant
    Public Images, Willich
    09/2016 – 11/2016 Waitress
    Seniorenzentrum, Willich

    Education

    04/2017 – 07/2019 M.Sc. Biology, Heinrich-Heine-Universität Düsseldorf
    Title of thesis: Impact of mononuclear phagocytes on myelin repair dynamics following stroke
    Focus in molecular biomedicine
    10/2013 – 03/2017 B.Sc. Biology, Heinrich-Heine-Universität Düsseldorf
    Title of thesis: Der „cystic fibrosis transmembrane conductance regulator“ (CFTR) und seine Rolle bei der Entstehung von Mukoviszidose
    08/2011 – 06/2013 Germ. High School Degree („Abitur“),
    Robert Schuman Europaschule Willich
    Advanced Courses:
    German, Mathematics
    Examination subjects:
    Biology, Pedagogy
    08/2004 – 07/2013 High School entrance qualification,
    Willi-Graf-Realschule Willich
    08/2000 – 07/2004 Astrid Lindgren Elementary School Hilden

    Skills

    Languages  
      German, native
      English, fluent
      French, basic
    IT skills  
      MS Office, very good
      GraphPad, very good
      ImageJ, very good
      PubMed, very good
    Practical skills  
      FELASA Function A & D
    Technical skills  
      Establishment of organotypic slice culture
      Operation cerebral photothrombosis in mice
      Immunocytochemistry, Immunohistochemistry
      Paraffin sections, Frozen sections
      Quantitative real-time PCR
      Blood sample preparation for FACS sorting
      Microscopic investigation and analysis

  • Publications

    2023

    1. Vinnenberg, L.*, Rychlik, N.*, Oniani, T.*, Williams, B., White, J. A., Kovac, S., Meuth, S. G., Budde, T., & Hundehege, P. (2023). Assessing neuroprotective effects of diroximel fumarate and siponimod via modulation of pacemaker channels in an experimental model of remyelination. Experimental Neurology, 371. doi.org/10.1016/j.expneurol.2023.114572. *equal contribution

    2.  H. Kapell*, L. Fazio*, J. Dyckow*, S. Schwarz, A. Cruz-Herranz, J. Campos, C. Mayer, E. D´Este, W. Möbius, C. Cordano, A.-K. Pröbstel, M. Gharagozloo, A. Zulji, V. Narayanan Naik, A. Delank, M. Cerina, T. Müntefering, C. Lerma-Martin, J. K. Sonner, J. H. Sin, P. Disse, N. Rychlik, K. Sabeur, M. Chavali, R. Srivastava, M. Heidenreich, K. C. Fitzgerald, G. Seebohm, C. Stadelmann, B. Hemmer, M. Platten, T. J. Jentsch, M. Engelhardt, T. Budde, K.-A. Nave, P. A. Calabresi, M. A. Friese, A. J. Green, C. Acuna, D. H. Rowitch, S. G. Meuth, L. Schirmer (2023). Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier as a neuroprotective target during inflammatory demyelination. Journal of Clinical Investigation, 133: e164223. doi: 10.1172/JCI164223. *equal contribution 

    3.  Werner, L.*, Gliem, M.*, Rychlik, N., Pavic, G., Reiche, L., Kirchhoff, F., Silva Oliveira Junior, M., Gruchot, J., Meuth, S. G., Küry, P., & Göttle, P. (2023). A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage. International Journal of Molecular Sciences, 24(13), 10972. https://doi.org/10.3390/ijms241310972

    4.  Göttle, P., Groh, J., Reiche, L., Gruchot, J., Rychlik, N., Werner, L., Samper Agrelo, I., Akkermann, R., Zink, A., Prigione, A., Hartung, H. P., Martini, R., & Küry, P. (2023). Teriflunomide as a therapeutic means for myelin repair. Journal of Neuroinflammation, 20(1). doi.org/10.1186/s12974-022-02686-6

    2022

    1. Rychlik, N., Hundehege, P., & Budde, T. (2022). Influence of inflammatory processes on thalamocortical activity. In Biological Chemistry. De Gruyter Open Ltd. doi.org/10.1515/hsz-2022-0215

    2021

    1.  Pavic, G., Petzsch, P., Jansen, R., Raba, K., Rychlik, N., Simiantonakis, I., Küry, P., Göttle, P., Köhrer, K., Hartung, H. P., Meuth, S. G., Jander, S., & Gliem, M. (2021). Microglia contributes to remyelination in cerebral but not spinal cord ischemia. GLIA, 69(11), 2739–2751. doi.org/10.1002/glia.24068