Berri, F., Haffar, G., Lê, V.B., Sadewasser, A., Paki, K., Lina, B, Wolff, T. and B. Riteau (2014). Annexin V incorporated into influenza virus particles inhibits interferon-ß signaling and promotes viral replication. (2014). Journal of Virology Jul 16. pii: JVI.01405-14.Börgeling Y, Schmolke M, Viemann D, Nordhoff C, Roth J, Ludwig S. Inhibition of p38 Mitogen-activated Protein Kinase Impairs Influenza Virus-induced Primary and Secondary Host Gene Responses and Protects Mice from Lethal H5N1 Infection. (2014). J Biol Chem. 289(1):13-27.Brunotte L, Flies J, Bolte H, Reuther P, Vreede F, Schwemmle M. The nuclear export protein of H5N1 influenza A viruses recruits Matrix 1 (M1) protein to the viral ribonucleoprotein to mediate nuclear export. (2014). J Biol Chem. Jul 18;289(29):20067-77.Czudai-Matwich V, Otte A, Matrosovich M, Gabriel G, Klenk HD (2014). PB2 Mutations D701N and S714R Promote Adaptation of an Influenza H5N1 Virus to a Mammalian Host. (2014). J. Virol., 88(16):8735-42.Dengler, L., Kuhn, N., Shin, D.L., Hatesuer, B., Schughart, K., and Wilk, E. Cellular changes in blood indicate severe respiratory disease during influenza infections in mice. (2014). PLoS ONE 9, e103149.Derksen A, Hensel A, Hafezi W, Herrmann F, Schmidt TJ, Ehrhardt C, Ludwig S, Kühn J. 3-O-Galloylated Procyanidins from Rumex acetosa L. Inhibit the Attachment of Influenza A Virus. (2014). PLoS One. 2014 Oct 10;9(10):e110089.Dierkes R, Warnking K, Liedmann S, Seyer R, Ludwig S, Ehrhardt C. The Rac1 inhibitor NSC23766 exerts anti-influenza virus properties by affecting the viral polymerase complex activity. (2014). PLoS One. Feb 11;9(2):e88520. doi: 10.1371/journal.pone.0088520. Dimitrakopoulou, K., Dimitrakopoulos, G.N., Wilk, E., Tsimpouris, C., Sgarbas, K.N., Schughart, K., and Bezerianos, A. Influenza A Immunomics and Public Health Omics: The Dynamic Pathway Interplay in Host Response to H1N1 Infection. (2014a). OMICS 18, 167-183.Fereidouni SR, Harder TC, Globig A, Starick E. Failure of productive infection of Mallards (Anas platyrhynchos) with H16 subtype of avian influenza viruses. (2014). Influenza Other Respir Viruses. Nov;8(6):613-6. doi: 10.1111/irv.12275. Epub 2014 Sep 10. PubMed PMID: 25205059.
Fereidouni S, Kwasnitschka L, Balkema Buschmann A, Müller T, Freuling C, Schatz J, Pikula J, Bandouchova H, Hoffmann R, Ohlendorf B, Kerth G, Tong S, Donis R, Beer M, Harder T. No Virological Evidence for an Influenza A – like Virus in European Bats. (2014). Zoonoses Public Health. May 17. doi: 10.1111/zph.12131. [Epub ahead of print] PubMed PMID: 24837569.
Gabriel G and Arck PC. Sex, Immunity and Influenza. (2014). J. Infect. Dis., 209 Suppl 3:S93-9.
Gabriel G and Fodor E. Molecular determinants of pathogenicity in the polymerase complex. (2014). Curr. Top. Microbiol. Immunol., 385:35-60.
Grienke, U., Braun, H., Seidel, N., Kirchmair, J., Richter, M., Krumbholz, A., von Grafenstein, S., Liedl, K., Schmidtke, M., Rollinger, J.M. A Computer-guided approach to access the anti-influenza activity of Licorice constituents. (2014). J. Nat. Prod., 77(3):563-70.
Groth M, Lange J, Kanrai P, Pleschka S, Scholtissek C, Krumbholz A, Platzer M, Sauerbrei A, Zell R. The genome of an influenza virus from a pilot whale: relation to influenza viruses of gulls and marine mammals. (2014). Infect Genet Evol. Jun;24:183-6.
Han Q, Chang C, Li L, Klenk C, Cheng J, Chen Y, Xia N, Shu Y, Chen Z, Gabriel G, Sun B, Xu K. Sumoylation of influenza A virus nucleoprotein is essential for intracellular trafficking and virus growth. (2014). J. Virol., 88(16):9379-90.
Haasbach E, Hartmayer C, Hettler A, Sarnecka A, Wulle U, Ehrhardt C, Ludwig S, Planz O. Antiviral activity of Ladania067, an extract from wild black currant leaves against influenza A virus in vitro and in vivo. (2014). Front Microbiol. Apr 22;5:171.
Herold S, Hoegner K, Vadász I, Gessler T, Wilhelm J, Mayer K, Morty RE, Walmrath HD, Seeger W, Lohmeyer J. Inhaled GM-CSF as treatment of pneumonia-associated acute respiratory distress syndrome. (2014). Am J Respir Crit Care Med. Mar 1;189(5):609-11.
Hillesheim A, Nordhoff C, Boergeling Y, Ludwig S, Wixler V. β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling. (2014). Cell Commun Signal. Apr 26;12:29.
Himanshu, M., Seidel, N., Krumbholz, A., Sauerbrei, A., Schmidtke, M., Guthke, R. Within-host influenza dynamics: a small-scale mathematical modeling approach. (2014). BioSystems, 118:51-9.
Hoffmann J, Schneider C, Heinbockel L, Brandenburg K, Reimer R and Gabriel G. A New Class of Synthetic Anti-Lipopolysaccharide Peptides Inhibits Influenza A Virus Replication by Blocking Cellular Attachment. (2014). Antiviral Res., 104:23-33.
Hrincius, E.R., Liedmann, S., Anhlan, D., Wolff, T., Ludwig, S. and C. Ehrhardt. Avian influenza viruses inhibit the major cellular signaling integrator c-Abl. (2014). Cellular Microbiology 16(12). 1854-74.
Hrincius ER, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Ehrhardt C, Ludwig S, Hains DS, Webby R, McCullers JA. NS1 mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic? (2014). J Infect Dis. Nov 2. pii: jiu609. [Epub ahead of print].
Juozapaitis M, Aguiar Moreira É, Mena I, Giese S, Riegger D, Pohlmann A, Höper D, Zimmer G, Beer M, García-Sastre A, Schwemmle M. An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus. (2014). Nat Commun. Jul 23;5:4448.
Kalthoff D, Bogs J, Grund C, Tauscher K, Teifke JP, Starick E, Harder T, Beer M. Avian influenza H7N9/13 and H7N7/13: a comparative virulence study in chickens, pigeons, and ferrets. (2014). J Virol. Aug;88(16):9153-65. doi: 10.1128/JVI.01241-14. Epub 2014 Jun 4. PubMed PMID: 24899194; PubMed Central PMCID: PMC4136250.
Kalthoff D, Bogs J, Harder T, Grund C, Pohlmann A, Beer M, Hoffmann B. Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus. (2014). Euro Surveill. Mar 13;19(10). pii: 20731. PubMed PMID: 24650867.
Köther K, Nordhoff C, Masemann D, Varga G, Bream JH, Gaestel M, Wixler V, Ludwig S. MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection. (2014). FASEB J. Oct;28(10):4235-46.
Kollmus, H., Wilk, E., and Schughart, K. Systems biology and systems genetics-novel innovative approaches to study host-pathogen interactions during influenza infection. (2014). Curr Opin Virol 6C, 47-54.
Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD. Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A. (2014). J Med Chem. 57:4629-4639. doi:10.1021/jm500598u. PMID: 24793875.
Krumbholz A, Lange J, Sauerbrei A, Groth M, Platzer M, Kanrai P, Pleschka S, Scholtissek C, Büttner M, Dürrwald R, Zell R. The origin of the European avian-like swine influenza viruses. (2014). J Gen Virol. Nov;95(Pt 11):2372-6. doi: 10.1099/vir.0.068569-0. Epub 2014 Jul 29.
Krumbholz A, Lange J, Dürrwald R, Walther M, Müller TH, Kühnel D, Wutzler P, Sauerbrei A, Zell R. Prevalence of antibodies to European porcine influenza viruses in humans living in high pig density areas of Germany. (2014). Med Microbiol Immunol. 203(1):13-24. doi: 10.1007/s00430-013-0309-y. Epub 2013 Sep 8. PMID:24013183.
Lange J, Groth M, Kanrai P, Pleschka S, Scholtissek C, Dürrwald R, Platzer M, Sauerbrei A, Zell R. Circulation of classical swine influenza virus in Europe between the wars? (2014). Arch Virol in press. 2013 Dec 15. [Epub ahead of print].
Liedmann, S., Hrincius, E.R., Guy, C., Anhlan, D., Dierkes, R., Carter, R., Wu, G., Staeheli, P., Green, D.R., Wolff, T., McCullers, J.A., Ludwig, S. and C. Ehrhardt. Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions. (2014). Nature Communications, Doi 10.1038/ncomm6645.
Liedmann S, Hrincius ER, Anhlan D, McCullers JA, Ludwig S, Ehrhardt C. New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant. (2014). J Infect Dis. Feb 15;209(4):532-41.
Liu, F.D.M., Kenngott, E.E., Schröter, M.F., Kühl, A., Jennrich S., Watzlawick, R., Hoffmann, U., Wolff, T., Norley, S., Scheffold, A., Stumhofer, J.S., Saris, C.J.M., Schwab, J.M., Hunter, C.A., Debes, G.F., and A. Hamann. Timed action of IL-27 protects from immunopathology while preserving defense in influenza. (2014). Plos Pathogens 10(5):e1004110.
Ludwig S, Zell R, Schwemmle M, Herold S. Influenza, a One health paradigm – novel therapeutic strategies to fight a zoonotic pathogen with pandemic potential. (2014). Int J Med Microbiol, 304(7):894-901. (Review)
Ludwig S. Will omics help to cure the flu? (2014). Trends Microbiol. May;22(5):232-3. (Review)
Meiners C, Loesken S, Doehring S, Starick E, Pesch S, Maas A, Noe T, Beer M, Harder T, Grosse Beilage E. Field study on swine influenza virus (SIV) infection in weaner pigs and sows. (2014). Tierarztl Prax Ausg G Grosstiere Nutztiere. Nov 18;42(6). [Epub ahead of print] PubMed PMID: 25405955.
Nacken, W., Anhlan, D., Hrincius, E.R., Mostafa, A., Wolff, T., Sadewasser, A., Pleschka, S., Ehrhardt, C., Ludwig, S. Activation of c-jun N-terminal kinase upon Influenza A Virus (IAV) infection is independent of pathogen related receptors, but dependent on amino acid sequence variations of the IAV NS1. (2014). Journal of Virology 15; 88(16):8843-8852.
Rakers, C., Schwerdtfeger, S.M., Mortier, J., Duwe, S., Wolff, T., Wolber, G. and Melzig, M.F. (2014). Bioorganic & Medicinal Chemistry Letters , Jul 18. pii: S0960-894X(14)00734-3. doi: 10.1016/j.bmcl.2014.07.010.
Resa-Infante P, Thieme R, Ernst T, Arck PC, Ittrich H, Reimer R, Gabriel G. Importin-α7 is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice. (2014). J. Virol., 88(14):8166-79.
Reuter A, Soubies S, Härtle S, Schusser B, Kaspers B, Staeheli P, Rubbenstroth D. Antiviral activity of lambda interferon in chickens. (2014). J Virol. 2014 Mar; 88(5):2835-43.
Reuther P, Giese S, Götz V, Kilb N, Mänz B, Brunotte L, Schwemmle M. Adaptive mutations in the nuclear export protein of human-derived H5N1 strains facilitate a polymerase activity-enhancing conformation. (2014). J Virol. Jan;88(1):263-71.
Schade, D., Kotthaus, J., Riebling, L., Müller-Fielitz, H., Raasch, W., Koch, O., Seidel, N., Schmidtke, M., Clement, B. Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A. (2014). J Med. Chem., 57:759-69.
Schmidtke, M., Mertens, T. Brauchen wir die Grippemittel Tamiflu und Relenza? (2014). GMS Infect. Diseases, 2:ISSN 2195-8831.
Seidel, N., Wutzler, P., Sauerbrei, A., Schmidtke, M.Hemagglutinin 222D/G polymorphism facilitates fast intra-host evolution of pandemic (H1N1) 2009 influenza A viruses. (2014). PlosOne, 9(8), e1042333:1-13.
Siegers J, Short K, Leijten L, De Graaf M, Spronken M, Schrauwen E, Marshall N, Lowen A, Gabriel G, Osterhaus A, Kuiken T and van Riel D. Novel Avian-Origin Influenza A (H7N9) Virus Attachment to the Respiratory Tract of Five Animal Models. (2014). J. Virol., 88(8):4595-9.
Sauer, A.K., Liang, C.H., Stech, J., Peeters, B., Quéré, P., Schwegmann-Wessels, C., Wu, C.Y., Wong, C.H., G. Herrler. 2014. Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins. (2014). PLoS One. Feb 21;9(2):e89529. eCollection 2014.
Strengert M, Jennings R, Davanture S, Hayes P, Gabriel G, Knaus UG. Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection. (2014). Antioxid. Redox Signal., 20(17):2695-709.
Tarnow C, Engels G, Arendt A, Schwalm F, Sediri H, Preuss A, Neslon P, Garten W, Klenk HD, Gabriel G and Böttcher-Friebertshäuser E. TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice. (2014). J. Virol., 88(9):4744-51.
Tantawy, M.A., Hatesuer, B., Wilk, E., Dengler, L., Kasnitz, N., Weiss, S., and Schughart, K.The Interferon-Induced Gene Ifi27l2a is Active in Lung Macrophages and Lymphocytes After Influenza A Infection but Deletion of Ifi27l2a in Mice Does Not Increase Susceptibility to Infection. (2014). PLoS ONE 9, e106392.
Van der Auwera S, Bulla I, Ziller M, Pohlmann A, Harder T, Stanke M. ClassyFlu: classification of influenza A viruses with Discriminatively trained profile-HMMs. (2014). PLoS One. Jan 3;9(1):e84558. doi: 10.1371/journal.pone.0084558. eCollection 2014. PubMed PMID: 24404173; PubMed Central PMCID: PMC3880301.
Vergara-Alert J, Busquets N, Ballester M, Chaves AJ, Rivas R, Dolz R, Wang Z, Pleschka S, Majó N, Rodríguez F, Darji A. The NS segment of H5N1 avian influenza viruses (AIV) enhances the virulence of an H7N1 AIV in chickens. (2014). Vet Res. Jan 25;45:7.
Warnking K, Klemm C, Löffler B, Niemann S, van Krüchten A, Peters G, Ludwig S, Ehrhardt C. Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signaling through impaired STAT1-STAT2 dimerization. (2014). Cell Microbiol. Oct 8. doi: 10.1111/cmi.12375.Zhou Z, Cao M, Guo Y, Zhao L, Wang J, Jia X, Li J, Wang C, Gabriel G, Xue Q, Yi Y, Cui S, Jin Q, Wang J and Deng T. Fragile X Mental Retardation Protein Stimulates Ribonucleoprotein Assembly of Influenza A Virus. (2014). Nat. Commun., 5:3259.
Fereidouni S, Kwasnitschka L, Balkema Buschmann A, Müller T, Freuling C, Schatz J, Pikula J, Bandouchova H, Hoffmann R, Ohlendorf B, Kerth G, Tong S, Donis R, Beer M, Harder T. No Virological Evidence for an Influenza A – like Virus in European Bats. (2014). Zoonoses Public Health. May 17. doi: 10.1111/zph.12131. [Epub ahead of print] PubMed PMID: 24837569.
Gabriel G and Arck PC. Sex, Immunity and Influenza. (2014). J. Infect. Dis., 209 Suppl 3:S93-9.
Gabriel G and Fodor E. Molecular determinants of pathogenicity in the polymerase complex. (2014). Curr. Top. Microbiol. Immunol., 385:35-60.
Grienke, U., Braun, H., Seidel, N., Kirchmair, J., Richter, M., Krumbholz, A., von Grafenstein, S., Liedl, K., Schmidtke, M., Rollinger, J.M. A Computer-guided approach to access the anti-influenza activity of Licorice constituents. (2014). J. Nat. Prod., 77(3):563-70.
Groth M, Lange J, Kanrai P, Pleschka S, Scholtissek C, Krumbholz A, Platzer M, Sauerbrei A, Zell R. The genome of an influenza virus from a pilot whale: relation to influenza viruses of gulls and marine mammals. (2014). Infect Genet Evol. Jun;24:183-6.
Han Q, Chang C, Li L, Klenk C, Cheng J, Chen Y, Xia N, Shu Y, Chen Z, Gabriel G, Sun B, Xu K. Sumoylation of influenza A virus nucleoprotein is essential for intracellular trafficking and virus growth. (2014). J. Virol., 88(16):9379-90.
Haasbach E, Hartmayer C, Hettler A, Sarnecka A, Wulle U, Ehrhardt C, Ludwig S, Planz O. Antiviral activity of Ladania067, an extract from wild black currant leaves against influenza A virus in vitro and in vivo. (2014). Front Microbiol. Apr 22;5:171.
Herold S, Hoegner K, Vadász I, Gessler T, Wilhelm J, Mayer K, Morty RE, Walmrath HD, Seeger W, Lohmeyer J. Inhaled GM-CSF as treatment of pneumonia-associated acute respiratory distress syndrome. (2014). Am J Respir Crit Care Med. Mar 1;189(5):609-11.
Hillesheim A, Nordhoff C, Boergeling Y, Ludwig S, Wixler V. β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling. (2014). Cell Commun Signal. Apr 26;12:29.
Himanshu, M., Seidel, N., Krumbholz, A., Sauerbrei, A., Schmidtke, M., Guthke, R. Within-host influenza dynamics: a small-scale mathematical modeling approach. (2014). BioSystems, 118:51-9.
Hoffmann J, Schneider C, Heinbockel L, Brandenburg K, Reimer R and Gabriel G. A New Class of Synthetic Anti-Lipopolysaccharide Peptides Inhibits Influenza A Virus Replication by Blocking Cellular Attachment. (2014). Antiviral Res., 104:23-33.
Hrincius, E.R., Liedmann, S., Anhlan, D., Wolff, T., Ludwig, S. and C. Ehrhardt. Avian influenza viruses inhibit the major cellular signaling integrator c-Abl. (2014). Cellular Microbiology 16(12). 1854-74.
Hrincius ER, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Ehrhardt C, Ludwig S, Hains DS, Webby R, McCullers JA. NS1 mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic? (2014). J Infect Dis. Nov 2. pii: jiu609. [Epub ahead of print].
Juozapaitis M, Aguiar Moreira É, Mena I, Giese S, Riegger D, Pohlmann A, Höper D, Zimmer G, Beer M, García-Sastre A, Schwemmle M. An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus. (2014). Nat Commun. Jul 23;5:4448.
Kalthoff D, Bogs J, Grund C, Tauscher K, Teifke JP, Starick E, Harder T, Beer M. Avian influenza H7N9/13 and H7N7/13: a comparative virulence study in chickens, pigeons, and ferrets. (2014). J Virol. Aug;88(16):9153-65. doi: 10.1128/JVI.01241-14. Epub 2014 Jun 4. PubMed PMID: 24899194; PubMed Central PMCID: PMC4136250.
Kalthoff D, Bogs J, Harder T, Grund C, Pohlmann A, Beer M, Hoffmann B. Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus. (2014). Euro Surveill. Mar 13;19(10). pii: 20731. PubMed PMID: 24650867.
Köther K, Nordhoff C, Masemann D, Varga G, Bream JH, Gaestel M, Wixler V, Ludwig S. MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection. (2014). FASEB J. Oct;28(10):4235-46.
Kollmus, H., Wilk, E., and Schughart, K. Systems biology and systems genetics-novel innovative approaches to study host-pathogen interactions during influenza infection. (2014). Curr Opin Virol 6C, 47-54.
Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD. Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A. (2014). J Med Chem. 57:4629-4639. doi:10.1021/jm500598u. PMID: 24793875.
Krumbholz A, Lange J, Sauerbrei A, Groth M, Platzer M, Kanrai P, Pleschka S, Scholtissek C, Büttner M, Dürrwald R, Zell R. The origin of the European avian-like swine influenza viruses. (2014). J Gen Virol. Nov;95(Pt 11):2372-6. doi: 10.1099/vir.0.068569-0. Epub 2014 Jul 29.
Krumbholz A, Lange J, Dürrwald R, Walther M, Müller TH, Kühnel D, Wutzler P, Sauerbrei A, Zell R. Prevalence of antibodies to European porcine influenza viruses in humans living in high pig density areas of Germany. (2014). Med Microbiol Immunol. 203(1):13-24. doi: 10.1007/s00430-013-0309-y. Epub 2013 Sep 8. PMID:24013183.
Lange J, Groth M, Kanrai P, Pleschka S, Scholtissek C, Dürrwald R, Platzer M, Sauerbrei A, Zell R. Circulation of classical swine influenza virus in Europe between the wars? (2014). Arch Virol in press. 2013 Dec 15. [Epub ahead of print].
Liedmann, S., Hrincius, E.R., Guy, C., Anhlan, D., Dierkes, R., Carter, R., Wu, G., Staeheli, P., Green, D.R., Wolff, T., McCullers, J.A., Ludwig, S. and C. Ehrhardt. Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions. (2014). Nature Communications, Doi 10.1038/ncomm6645.
Liedmann S, Hrincius ER, Anhlan D, McCullers JA, Ludwig S, Ehrhardt C. New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant. (2014). J Infect Dis. Feb 15;209(4):532-41.
Liu, F.D.M., Kenngott, E.E., Schröter, M.F., Kühl, A., Jennrich S., Watzlawick, R., Hoffmann, U., Wolff, T., Norley, S., Scheffold, A., Stumhofer, J.S., Saris, C.J.M., Schwab, J.M., Hunter, C.A., Debes, G.F., and A. Hamann. Timed action of IL-27 protects from immunopathology while preserving defense in influenza. (2014). Plos Pathogens 10(5):e1004110.
Ludwig S, Zell R, Schwemmle M, Herold S. Influenza, a One health paradigm – novel therapeutic strategies to fight a zoonotic pathogen with pandemic potential. (2014). Int J Med Microbiol, 304(7):894-901. (Review)
Ludwig S. Will omics help to cure the flu? (2014). Trends Microbiol. May;22(5):232-3. (Review)
Meiners C, Loesken S, Doehring S, Starick E, Pesch S, Maas A, Noe T, Beer M, Harder T, Grosse Beilage E. Field study on swine influenza virus (SIV) infection in weaner pigs and sows. (2014). Tierarztl Prax Ausg G Grosstiere Nutztiere. Nov 18;42(6). [Epub ahead of print] PubMed PMID: 25405955.
Nacken, W., Anhlan, D., Hrincius, E.R., Mostafa, A., Wolff, T., Sadewasser, A., Pleschka, S., Ehrhardt, C., Ludwig, S. Activation of c-jun N-terminal kinase upon Influenza A Virus (IAV) infection is independent of pathogen related receptors, but dependent on amino acid sequence variations of the IAV NS1. (2014). Journal of Virology 15; 88(16):8843-8852.
Rakers, C., Schwerdtfeger, S.M., Mortier, J., Duwe, S., Wolff, T., Wolber, G. and Melzig, M.F. (2014). Bioorganic & Medicinal Chemistry Letters , Jul 18. pii: S0960-894X(14)00734-3. doi: 10.1016/j.bmcl.2014.07.010.
Resa-Infante P, Thieme R, Ernst T, Arck PC, Ittrich H, Reimer R, Gabriel G. Importin-α7 is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice. (2014). J. Virol., 88(14):8166-79.
Reuter A, Soubies S, Härtle S, Schusser B, Kaspers B, Staeheli P, Rubbenstroth D. Antiviral activity of lambda interferon in chickens. (2014). J Virol. 2014 Mar; 88(5):2835-43.
Reuther P, Giese S, Götz V, Kilb N, Mänz B, Brunotte L, Schwemmle M. Adaptive mutations in the nuclear export protein of human-derived H5N1 strains facilitate a polymerase activity-enhancing conformation. (2014). J Virol. Jan;88(1):263-71.
Schade, D., Kotthaus, J., Riebling, L., Müller-Fielitz, H., Raasch, W., Koch, O., Seidel, N., Schmidtke, M., Clement, B. Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A. (2014). J Med. Chem., 57:759-69.
Schmidtke, M., Mertens, T. Brauchen wir die Grippemittel Tamiflu und Relenza? (2014). GMS Infect. Diseases, 2:ISSN 2195-8831.
Seidel, N., Wutzler, P., Sauerbrei, A., Schmidtke, M.Hemagglutinin 222D/G polymorphism facilitates fast intra-host evolution of pandemic (H1N1) 2009 influenza A viruses. (2014). PlosOne, 9(8), e1042333:1-13.
Siegers J, Short K, Leijten L, De Graaf M, Spronken M, Schrauwen E, Marshall N, Lowen A, Gabriel G, Osterhaus A, Kuiken T and van Riel D. Novel Avian-Origin Influenza A (H7N9) Virus Attachment to the Respiratory Tract of Five Animal Models. (2014). J. Virol., 88(8):4595-9.
Sauer, A.K., Liang, C.H., Stech, J., Peeters, B., Quéré, P., Schwegmann-Wessels, C., Wu, C.Y., Wong, C.H., G. Herrler. 2014. Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins. (2014). PLoS One. Feb 21;9(2):e89529. eCollection 2014.
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