Dr. rer. nat. Birgit Stallmeyer


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Tel.: +49 (251) 83 - 53234
E-Mail: Birgit Stallmeyer
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  • University training and degree

    1994 Diploma in Biology; Topic: Isolation and functional characterisation of a cDNA in A.thaliana that functionally complements the E.coli mutant mogA
    1990 – 1994 Studies in Biology, Technical University of Braunschweig
    1988 – 1990 Studies in Biology, University of Münster

  • Advanced academic qualifications

    1998 Award of PhD (Dr. rer. nat.), Grade: Summa cum laude; Topic: Identification and functional characterization of human cDNAs involved in Molybdenum cofactor synthesis
    1994 – 1998 PhD at the Institute of Botany, Technical University Braunschweig

  • Postgraduate professional career

    2022 – Group Leader at the Institute of Reproductive Genetics (IRG), University of Münster
    2021 – Senior Scientist at the Institute of Reproductive Genetics (IRG), University of Münster
    2007 – 2021 Senior Scientist at the Institute for Genetics of Heart Diseases (IfGH), UKM
    2001 – 2003 Post-Doctoral Researcher at the Leibnitz Institute of Arteriosclerosis Research, Münster
    1998 – 2000 Post-Doctoral Researcher at the Institute of Pharmacology and Toxicology, University Hospital Frankfurt am Main

  • Academic memberships and activities

    2021 – Equal Opportunity Representative of the Clinical Research Unit CRU326 ‘Male Germ Cells’
    2012 – 2016 Deputy Quality Manager at the Institute for Genetics of Heart Diseases (DIN ISO 15189:2014)

  • Selected publications

    All publications by Dr. rer. nat. Birgit Stallmeyer can be found here.

    1. Stallmeyer B, Bühlmann C, Stakaitis R, Dicke AK, Ghieh F, Meier L, Zoch A, MacKenzie MacLeod D, Steingröver J, Okutman Ö, Fietz D, Pilatz A, Riera-Escamilla A, Xavier MJ, Ruckert C, Di Persio S, Neuhaus N, Gurbuz AS, Şalvarci A, Le May N, McEleny K, Friedrich C, van der Heijden G, Wyrwoll MJ, Kliesch S, Veltman JA, Krausz C, Viville S, Conrad DF, O'Carroll D, Tüttelmann F. Inherited defects of piRNA biogenesis cause transposon de-repression, impaired spermatogenesis, and human male infertility. Nat Commun. 2024 Aug 9;15(1):6637. doi: 10.1038/s41467-024-50930-9.
    2. Stallmeyer B, Dicke AK, Tüttelmann F. How exome sequencing improves the diagnostics and management of men with non-syndromic infertility. Andrology. 2024 Aug 9. doi: 10.1111/andr.13728.
    3. Dicke A-K, Albrethsen J, Hoare BL, Wyrwoll MJ, Busch AS, Fietz D, Pilatz A, Bühlmann C, Juul A, Kliesch S, Gromoll J, Bathgate RAD, Tüttelmann F*, Stallmeyer B*. Bi-allelic variants in INSL3 and RXFP2 cause bilateral cryptorchidism and male infertility. Hum Reprod. 38:1412-1423, 2023.
    4. Dicke AK, Pilatz A, Wyrwoll MJ, Punab M, Ruckert C, Nagirnaja L, Aston KI, Conrad DF, Di Persio S, Neuhaus N, Fietz D, Laan M, Stallmeyer B*, Tüttelmann F*. DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia. Commun Biol. 6(1): 350, 2023.
    5. Kuß J*, Stallmeyer B*, Goldstein M, Rinné S, Pees C, Zumhagen S, Seebohm G, Decher N, Pott L, Kienitz MC, Schulze-Bahr E. Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K+ Channel) Channel Function. Circ Genom Precis Med. 12(1): e002238, 2019.
    6. Stallmeyer B*, Kuss J*, Kotthoff S, Zumhagen S, Vowinkel K, Rinne S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N, Schulze-Bahr E. A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. Circ Res. 120: e33-e44, 2018.
    7. Stallmeyer B, Zumhagen S, Denjoy I, Duthoit G, Hebert JL, Ferrer X, Maugenre S, Schmitz W, Kirchhefer U, Schulze-Bahr E, Guicheney P, Schulze-Bahr E. Mutational spectrum in the Ca(2+)-activated cation channel gene TRPM4 in patients with cardiac conductance disturbances. Hum Mutat. 33: 109-17, 2012.
    8. Stallmeyer B, Fenge H, Nowak-Gottl U, Schulze-Bahr E. Mutational spectrum in the cardiac transcription factor gene NKX2.5 (CSX) associated with congenital heart disease. Clinical Genetics. 78: 533-40, 2010.
    9. Stallmeyer B, Schwarz G, Schulze J, Nerlich A, Reiss J, Kirsch J, Mendel RR. The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells. Proc Natl Acad Sci U S A. 96: 1333-8, 1999.
    10. Stallmeyer B, Drugeon G, Reiss J, Haenni AL, Mendel RR. Human molybdopterin synthase gene: identification of a bicistronic transcript with overlapping reading frames. American Journal of Human Genetics. 64: 698-705, 1999.

    * contributed equally