Since 2012, the IZKF Münster has supported a total of 20 research-enthusiastic young doctors in this funding format developed specifically for Clinician Scientists. This funding module provided young clinicians with the opportunity of rotating out of the clinic for 3 years and to work on their own scientific project at a self-selected preclinical or clinical-theoretical institute, to expand their scientific expertise and to take on initial responsibility for a small working group.

In 2022, the IZKF board decided to integrate the successful funding format into the DFG-funded Clinician Scientist program CareerS, which has now been established at the Medical Faculty. The goal is to offer a common career path for doctors in the faculty, in which different funding partners participate.

The SEED.projects that will continue to be funded until December 2023 and 2025 respectively, have been integrated into the CareerS community. As of 2023, the IZKF no longer announces calls for the Clinicial scientist programme format SEED.projects.

Currently funded SEED projects:

• SEED/018/23 - Mitigation of JAM-dependent transendothelial and reverse transendothelial migration (rTEM) of T2DM monocytes/macrophages as a novel strategy to decelerate atherosclerosis development in diabetes mellitus
  Group leader: Dilvin Semo
  Dispatching Clinic: Department of Cardiology I: Coronary heart disease, Cardiac insufficiency and Angiology
  Host Institute: Clinic for anaesthesiology, Surgical intensive care medicine and Pain therapy
  Funding period: 01/2023 - 12/2025

• SEED/019/23 - Surveillance and characterisation of antimicrobial resistance harbouring plasmids
  Group leader: Vincent van Almisck
  Dispatching Clinic: Department of Cardiology I: Coronary heart disease, Cardiac insufficiency and Angiology
  Host Institute: Institute of Hygiene
  Funding period: 01/2023 - 12/2025
• SEED/020/23 - cAIdiology - Artificial Intelligence for Precision Cardiology
  Group leader: Antonius Büscher
  Dispatching Clinic: Department of Cardiology I: Rhythmology
  Host Institute: Institute of Medical Informatics
  Funding period: 01/2023 - 12/2025
• SEED/021/23 - Assessment of the translational potential of Musashi RNA-binding protein inhibition in triple-negative breast cancer
  Group leader: Fabian Troschel
  Dispatching Clinic: Institute of Radiation Therapy Clinic - Radiation Oncology
  Host Institute: Institute of Radiation Therapy Clinic - Radiation Oncology
  Funding period: 01/2023 - 12/2025

• completed SEED projects

  • SEED/017/21 - Development and characterisation of a brain organoid model for a new autosomal recessive inherited defect of cortical malformation
    Group leader: Julia Wallmeier
    Dispatching clinic: Department of General Pediatrics
    Host institute: Max Planck Institute for Molecular Biomedicine
    Projektlaufzeit: 01/2021 - 12/2023
  • SEED/016/21 - Understanding human immune-mediated neuropathies at single cell resolution
    Group leader: Michael Heming
    Dispatching clinic: Division of Neurology
    Host institute: Institute of Medical Informatics
    Funding period: 01/2021 - 12/2023
  • SEED 015/20  - Direct reprogramming of kidney mesenchymal cells into podocytes as a therapeutic strategy for chronic kidney disease
    Group leader: Markus Carl Döser
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Max-Planck-Institute for Molecular Biomedicine
    Project duration: 01/2020-12/2022
  • SEED 014/20  - The impact of monocyte / macrophage SHP-2 tyrosine phosphatase on diabetes-induced atherosclerosis progression
    Group leader: Marc Dorenkamp
    Dispatching clinic: Department of Cardiovascular Medicine
    Host institute: European Institute for Molecular Imaging
    Project duration: 01/2020-12/2022
  • SEED 013/20  - BRD4 as novel epigenetic vulnerability of early T-cell precursor acute lymphoblastic leukemia (ETP-ALL)
    Group leader: Sebastian Balbach
    Dispatching clinic: Department of Pediatric Hematology and Oncology
    Host institute: Department of Pediatric Hematology and Oncology - Stem cell transplatation
    Project duration: 01/2020-12/2022
  • SEED 12/18 - The influence of platelet migration, thrombopoiesis and platelet subpopulations on the course of inflammation
    Group leader:  Andreas Margraf
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: AG Vascular Inflammation and Platelets
    Project duration: 09/2018-08/2021
  • SEED 11/19 - Individualised prediction of the clinical course of affective disorders by the use of integrated clinical and experimental data
    Group leader: Nils Opel
    Dispatching clinic: Department of Mental Health (formerly Department of Psychiatry and Psychotherapy)
    Host institute: Institute of Medical Informatics
    Project duration: 01/2019-12/2021
  • SEED 10/19 - The impact of the calcium-regulated K2P channel TRESK on T-cell functions in experimental stroke
    Group leader: Leoni Rolfes
    Dispatching clinic: Division of General Neurology
    Host institute: Institute for Translational Neurology
    Project duration: 01/2019 - 03/2021 (the project was terminated prematurely since the group leader moved to the University Hospital, Düsseldorf)
  • SEED 09/17 - Interleukin 24 in renal ischemia-reperfusion injury: Analysis of the pathophysiological role and evaluation of potential therapeutic options
    Group leader: Katharina Schütte-Nütgen
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Medical Biochemistry (ZMBE)
    Funding period: 01/2017 - 12/2019
  • SEED 07/17 - Leukocyte migration and endothelial integrity in cerebral ischaemia – pathophysiology, interaction, and relevance for outcome and secondary haemorrhage after intravenous thrombolysis
    Group leader: Antje Schmidt-Pogoda
    Dispatching clinic: Division of General Neurology
    Host institute: Max Planck Institute for Molecular Biomedicine

    Funding period: 01/2017 - 12/2019
  • SEED 06/15 - Analysis of the regulation of the actin cytoskelton in podocytes
    Group leader: Christopher Dlugos
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Cell Dynamics and Imaging
    Funding period: 01/2015 - 12/2017
  • SEED 05/15 - The role of GABAergic transmission and chloride homeostasis in pain development and processing
    Group leader: Tobias Schmidt
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Institute of Physiology I
    Funding period: 01/2015 - 12/2017 
  • SEED 04/12 - The role of L-selectin topography in integrin activation and lymphocyte homing
    Group leader: Konrad-Robert Buscher
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Institute of Physiological Chemistry and Pathobiochemistry
    Funding period: 04/2012 - 03/2014
  • SEED 03/12 - The role of K2P-channels (TASK1-3, TRESK) for intracellular signalling pathways in T-Lymphocytes
    Group leader: Stefan Bittner
    Dispatching clinic: Division of General Neurology
    Host institute: Institute of Physiology - Neuropathophysiology
    Funding period: 01/2012 - 12/2014
  • SEED 02/12 - Functional analysis of the WWC-protein family in epithelial cell polarity
    Group leader: Dirk Oliver Wennmann
    Dispatching clinic: Department of Medicine D - Nephrology and Rheumatology
    Host institute: Institute of Medical Biochemistry (ZMBE)
    Funding period: 01/2012 - 12/2014
  • SEED 01/12 - The role of growth-differentiation factor (GDF)-15 in platelet activation, thrombus formation and platelet-mediated inflammation
    Group leader: Jan Rossaint
    Dispatching clinic: Department of Anaesthesiology, Intensive Care and Pain Therapy
    Host institute: Max Planck Institute für Molecular Biomedicine
    Funding period: 01/2012 - 12/2014