PROJECTSInvolved Fellows1. Albrecht SchwabModulation of pressure sensing of pancreatic stellate cells by pancreatic pH. Micol Rugi micol.rugi(at)ukmuenster.de 2. Pawel SwietachModelling and understanding spatio-temporal pH dynamics in PDAC in silico using in vivo and in vitro data. Wiktoria Błaszczak w.z.blaszczak(at)gmail.com 3. Ivana NovakRole of pH and ATP signaling in normal pancreas and PDAC Ganga Deshar ganga.deshar(at)bio.ku.dk 4. Stine F. PedersenInteractions between microenvironmental acidity and PDAC driver mutations studied in 3D organotypic culture. Renata Ialchina renata.ialchina(at)bio.ku.dk 5. Albin SandelinRelation and causality between pH homeostasis and driver mutation generation in PDAC development. Jiayi Yao jiayi.yao(at)bio.ku.dk 6. Stephan J ReshkinRole of ECM composition and stromal cells in determining tumour and cancer stem cell pH/O2 handling and therapeutic response. Tiago Carvalho tiagomac94(at)gmail.com 7. Annarosa ArcangeliTargeting ion channel and adhesion receptor interaction during PDAC progression by pH-sensitive engineered antibodies. Franco D'Alessandro f.dalessandro1(at)student.unisi.it 8. Natalia PrevarskayaRole of Ca2+ permeable channels in PDAC and PSCs. Madelaine Magalì Audero madelaine.audero(at)gmail.com 9. Halima Ouadid-AhidouchExpression profiling of pH-regulatory and -sensitive transportome: epigenetic analysis and correlation with clinical parameters. Julie Schnipper julie_schnipper(at)hotmail.com 10. Luis PardoSimultaneous targeting of tumour cells and stroma by pH-sensitive engineered biologicals. Xiaoyi Shi shi(at)em.mpg.de 11. Frauke AlvesAssessment of physico-chemical parameters of PDAC by non-invasive imaging during tumour progression and in response to therapeutically targeting pH-dependent processes Jakub Mitręga mitrega(at)em.mpg.de 12. Anna TrauzoldAcquired nuclear functions of TRAIL-receptors as a consequence and motor of pH gradient reversal in PDAC. Sofie Emilie Hagelund sofie_hagelund(at)hotmail.com 13. György PanyiIon channels of immune cells and their regulation by the micro- environment in PDAC and its interface with normal tissue. Marco Cozzolino m.cozzolino91(at)outlook.it 14. Alan ChanMolecular imaging of the microenvironment-transportome interplay in PDAC Roisin Mc Morrow r.mcmorrow(at)erasmusmc.nl 15. Andreas PahlGeneration of PDAC specific ADCs and preclinical profiling. Elena Papacharisi elena.papacharisi(at)hdpharma.com