Robert-Koch-Str. 27 a
+ 49 251-83.55531 (phone)
+ 49 251-83.55551 (fax)
Annika.Luettjohann@ukmuenster.de

  • Curriculum vitae

    Education/Training:

    since 10/2022 Associated PI at ChemBion Graduate School (GRK 2515)
    7/2020 – present Academic Staff member (Akademische Rätin auf Zeit) at the Institute of Physiology I (Prof. Hans-Christian Pape), Westfälische Wilhelms University Münster
    8/2013 - 7/2020 Postdoctoral researcher at the Institute of Physiology I (Prof. Hans-Christian Pape), Westfälische Wilhelms University Münster
    2008-2013 Researcher within Dutch BrainGain Consortium,
    Project: Animal model for modulating brain activity: Deep Brain Stimulation in Absence epilepsy
    2008-2012 Ph.D., Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, The Netherlands (supervisor: Prof. E.L.J.M van Luijtelaar)
    Title of Dissertation: The role of the cortico-thalamo-cortical system in absence epilepsy - Unraveling brain networks using multi-site local field potential recordings, dynamical signal analysis and deep brain stimula
    2003-2008 Diploma (MSc), Psychology, Radboud University Nijmegen, The Netherlands (supervisor: Prof. E.L.J.M van Luijtelaar)
    1994-2003 Secondary school: ‘Städt. Willibrord-Gymnasium Emmerich’, Germany resulting in ‘Abitur’ (general qualification for universities)

  • Publications

    2023

    1. Ngomba RT, Lüttjohann A, Dexter A, Ray S, van Luijtelaar G (2023)
      The Metabotropic Glutamate 5 Receptor in Sleep and Wakefulness: Focus on the Cortico-Thalamo-Cortical Oscillations. Cells 12(13).

    2022

    1. Lüttjohann A, van Luijtelaar G (2022)
      The role of thalamic nuclei in genetic generalized epilepsies. Epilepsy Res. 1829: 1-17.

    2. Chaudhary R, Albrecht S, Datunashvili M, Cerina M, Lüttjohann A, Han Y, Narayanan V, Chetkovich DM, Ruck T, Kuhlmann T, Pape HC, Meuth SG, Zobeiri M, Budde T (2022)
      Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines. Cereb Cortex 32 (20): 4397-4421

    2021

    1. Wachsmuth L, Datunashvili M, Kemper K, Albers F, Lambers H, Lüttjohann A, Kreitz S, Budde T, Faber C (2021)
      Retrosplenial Cortex Contributes to Network Changes during Seizures in the GAERS Absence Epilepsy Rat Model. Cereb Cortex Commun. 23 (2).

    2. Reinscheid RK, Mafessoni F, Lüttjohann A, Jüngling K, Pape HC, Schulz S (2021)
      Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality. Peptides. 138:170506.

    3. Sysoev IV, van Luijtelaar G, Lüttjohann A (2021)
      Thalamo-Cortical and Thalamo-Thalamic Coupling During Sleep and Wakefulness in Rats. Brain Connect. [ahead of print].

    4. Budde B, Maksimenko V, Sarink K, Seidenbecher T, van Luijtelaar G, Hahn T, Pape HC, Lüttjohann A (2021)
      Seizure prediction in genetic rat models of absence epilepsy: improved performance through multiple-site cortico-thalamic recordings combined with machine learning. eNeuro 9 (1): 1-17.

    2020

    1. Terlau J, Yang JW, Khastkhodaei Z, Seidenbecher T, Luhmann HJ, Pape HC, Lüttjohann A (2020)
      Spike-wave discharges in absence epilepsy: segregation of electrographic components reveals distinct pathways of seizure activity. J Physiol. 598(12): 2397.

    2019

    1. Lüttjohann A, Pape HC (2019)
      Regional specificity of cortico-thalamic coupling strength and directionality during waxing and waning of spike and wave discharges. Sci Rep. 9(1): 2100.

    2018

    1. Zobeiri M, Chaudhary R, Datunashvili M, Heuermann RJ, Lüttjohann A, Narayanan V, Balfanz S, Meuth P, Chetkovich DM, Pape H-C, Baumann A, van Luijtelaar G, Budde T (2018)
      Modulation of thalamocortical oscillations by TRIP8b, a brain-specific auxiliary subunits for HCN channels. Brain Struct Funct. 223(3): 1537-1562.
    2. Datunashvili M, Chaudhary R, Zobeiri M, Lüttjohann A, Mergia E, Baumann A, Balfanz S, Budde B, van Luijtelaar G, Pape HC, Koesling D, Budde T (2018)
      Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides. Front Cell Neurosci. 12: 369.

    2017

    1. Maksimenko VA, van Heukelum S, Makarov VV, Kelderhuis J, Lüttjohann A, Koronovskii AA, Hramov AE, van Luijtelaar G (2017)
      Absence Seizure Control by a Brain Computer Interface. Sci Rep. 7(1): 2487.
    2. Lüttjohann A (2017)
      Disclosing hidden information in the electroencephalogram using advanced signal analytical techniques. J Physiol. 595(23): 7021-7022.
    3. Luijtelaar GV, Zobeiri M, Lüttjohann A, Depaulis A. (2017)
      Experimental Treatment Options in Absence Epilepsy. Curr Pharm Des. 23(37): 5577-5597.

    2016

    1. Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P, Pape HC (2016)
      Short term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. 2016 (in press)
    2. van Heukelum S, Kelderhuis J, Janssen P, van Luijtelaar G, Lüttjohann A (2016)
      Timing of high frequency cortical stimulation in a genetic absence model. Neuroscience. in press. doi:10.1016/j.neuroscience.2016.02070.
    3. Sysoeva MV, Lüttjohann A, van Luijtelaar G, Sysoev IV (2016)
      Dynamics of directional coupling underlying spike-wave discharges. Neuroscience. 314:75-89.
    4. van Luijtelaar G, Lüttjohann A, Makarov VV, Maksimenko VA, Koronovskii AA, Hramov AE (2016)
      Methods of automated absence seizure detection, interference by stimulation, and possibilities for prediction in genetic absence models. J Neurosci Methods. 260:144-58
    5. Russo E, Citraro R, Constanti A, Leo A, Lüttjohann A, van Luijtelaar G, De Sarro G. (2016)
      Upholding WAG/Rij rats as a model of absence epileptogenesis: Hidden mechanisms and a new theory on seizure development. Neurosci Behav Rev. 71: 388-408.

    2015

    1. Lüttjohann A, van Luijtelaar G (2015)
      Dynamics of networks during absence seizure's on- and offset in rodents and man. Front Physiol. 6:1-17

    2014

    1. Lüttjohann A, Schoffelen JM, van Luijtelaar G (2014)
      Termination of ongoing spike-wave discharges investigated by cortico-thalamic network analyses. Neurobiol Dis 70: 127-137

    2013

    1. Lüttjohann A, Schoffelen JM, van Luijtelaar G (2013)
      Peri-ictal network dynamics of spike-wave discharges: phase and spectral characteristics. Exp Neurol 239: 235-247
    2. Lüttjohann A, van Luijtelaar G (2013)
      Thalamic stimulation in absence epilepsy. Epilepsy Res 106: 136-145
    3. van Luijtelaar G, Mishra AM, Edelbroek P, Coman D, Frankenmolen N, Schaapsmeerders P, Covolato G, Danielson N, Niermann H, Janeczko K, Kiemeneij A, Burinov J, Bashyal C, Coquillette M, Lüttjohann A, Hyder F, Blumenfeld H, van Rijn CM (2013)
      Anti-epileptogenesis: Electrophysiology, diffusion tensor imaging and behavior in a genetic absence model. Neurobiol Dis 60: 126-138

    2012

    1. Lüttjohann A, van Luijtelaar G (2012)
      The dynamics of cortico-thalamo-cortical interactions at the transition from pre-ictal to ictal LFPs in absence epilepsy. Neurobiol Dis 47(1): 49-60

    2011

    1. Lüttjohann A, Zhang S, de Peijper R, van Luijtelaar G (2011)
      Electrical stimulation of the epileptic focus in absence epileptic WAG/Rij rats: assessment of local and network excitability. Neuroscience 188: 125-134
    2. van Luijtelaar G, Sitnikova E, Lüttjohann A (2011)
      On the origin and suddenness of absences in genetic absence models. Clin EEG Neurosci 42(2): 83-97 

    2010

    1. Ovchinnikov A, Lüttjohann A, Hramov A, van Luijtelaar G (2010)
      An algorithm for real-time detection of spike-wave discharges in rodents. J. Neurosci Methods 194(1): 172-178

    2009

    1. Lüttjohann A, Fabene PF, van Luijtelaar G (2009)
      A revised Racine's scale for PTZ-induced seizures in rats. Physiol Behav 98(5):579-86

  • Research Projects