Raised in a coastal city Zhuhai in southern China, I studied Biotechnology (Bachelor 2013-2017) and Biology (Master 2017-2020) at the Zhejiang Sci-Tech University.
During my bachelor study in Prof. Dr. Jianyi Pan’s Lab, I focused on the phosphorylation dynamics between wild-type Pseudomonas aeruginosa and an antibiotic-resistant strain to explore the potential kinase-substrate mechanism contributing to molecular drug-resistance.
My master thesis was supervised by Prof. Dr. Wei Yu. In that time, we concentrated on the post-translational modification (phosphorylation and acetylation) of viral or cellular proteins to figure out the molecular interaction between silkworms (Bombyx mori) and B. mori nucleopolyhedrovirus. My work mainly demonstrated that deacetylated HSC70-4 facilitates viral replication by UPS.
To enlarge my professional horizon, I continue my research on cellular virology in the Schelhaas group from November, 2021. My current study is to explore the key cellular factors required for HPV16 genome tethering to chromatin during mitosis.